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About: dbr:Interleukin_6     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Unit109465459, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingBiomoleculegeneBiomoleculeGeneyago:WikicatCytokinesyago:Abstraction100002137yago:Arrangement107938773yago:Chemical114806838yago:Compound114818238yago:Cytokine114828193yago:Gene105436752yago:Group100031264yago:Macromolecule114944888yago:Material114580897yago:Matter100020827yago:Molecule114682133yago:Ordering108456993yago:OrganicCompound114727670yago:Part113809207yago:PhysicalEntity100001930yago:Protein114728724yago:Relation100031921yago:WikicatGenesOnChromosome7HumanGeneproteinyago:Sequence108459252yago:Series108457976yago:Substance100019613yago:Thing100002452yago:Unit109465459 New Facet based on Instances of this Class

Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. In humans, it is encoded by the IL6 gene. In addition, osteoblasts secrete IL-6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL-6 as a pro-inflammatory cytokine. IL-6's role as an anti-inflammatory myokine is mediated through its inhibitory effects on TNF-alpha and IL-1 and its activation of IL-1ra and IL-10.