James Hepburn (died 1524) was a Scottish prelate and administrator. He was the son of Alexander Hepburn of Whitsome. His name occurs as the rector of Dalry and king's clerk on 1 August 1511. Hepburn was Treasurer of Scotland between from at least June 1515, until October the following year. He also held the position of rector of Parton in the diocese of Galloway. He was elected Bishop of Moray sometime before 12 February 1516, on the nomination of the Governor of Scotland, John Stewart, Duke of Albany, following the translation of Bishop Andrew Forman to the Archbishopric of St Andrews.