Joseph S. Clark Sr. High School was a high school in Tremé, New Orleans, Louisiana. Clark opened in 1947 as the first high school below Canal Street to educate colored children in New Orleans. It was named after Joseph S. Clark, the first president of the Southern University at Baton Rouge. The Rebirth Brass Band was formed at the high school in 1983. The high school was operated by the charter Firstline Schools at its closing in 2019.