About: Ketazocine

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Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor. Unlike other opioids, substances that only bind to the κ receptor theoretically do not depress the respiratory system. The crystal structure of ketazocine was determined in 1983.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Ketone114926294 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:Phenol114989545 yago:PhysicalEntity100001930 yago:Relation100031921 yago:WikicatKetones drug yago:Substance100019613 yago:WikicatPhenols umbel-rc:ChemicalSubstanceType
rdfs:label	Ketazocine (en) Chetazocina (it)
rdfs:comment	Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor. Unlike other opioids, substances that only bind to the κ receptor theoretically do not depress the respiratory system. The crystal structure of ketazocine was determined in 1983. (en) La chetazocina (INN), anche nota come chetociclazocina, è un derivato del benzomorfano utilizzato nella ricerca sui recettori oppioidi. La chetociclazocina è un oppioide esogeno che lega i recettori κ-oppioidi. (it)
foaf:depiction
dcterms:subject	Ketones Phenols Kappa-opioid receptor agonists Benzomorphans Synthetic opioids
Wikipage page ID	10059251 (xsd:integer)
Wikipage revision ID	1113856705 (xsd:integer)
Link from a Wikipage to another Wikipage	Benzomorphan Respiratory system Vasopressin Ketones Phenols Opioid receptor Kappa-opioid receptor agonists Benzomorphans Dysphoria Paranoia Endogenous Synthetic opioids Hallucinations International Nonproprietary Name Exogenous Ethylketazocine Κ opioid receptor
sameAs	Ketazocine Ketazocine Ketazocine Ketazocine Ketazocine Ketazocine Ketazocine
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Hallucinogens dbt:Opioidergics dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite
thumbnail	wiki-commons:Special:FilePath/Ketazocine_structure.svg?width=300
ATC prefix	none (en)
c	18 (xsd:integer)
CAS number	36292 (xsd:integer)
ChemSpiderID	2316328 (xsd:integer)
H	23 (xsd:integer)
IUPAC name	-3 (xsd:integer)
KEGG	D04649 (en)
n	1 (xsd:integer)
O	2 (xsd:integer)
PubChem	3054741 (xsd:integer)
routes of administration	Oral (en)
SMILES	O=C2c1c[C@]3C (en)
StdInChI	1 (xsd:integer)
StdInChIKey	HQBZLVPZOGIAIQ-SDDDUWNISA-N (en)
UNII	6 (xsd:integer)
verifiedrevid	443949789 (xsd:integer)
has abstract	Ketazocine (INN), also known as ketocyclazocine, is a benzomorphan derivative used in opioid receptor research. Ketazocine, for which the receptor is named, is an exogenous opioid that binds to the κ opioid receptor. Activation of this receptor is known to cause sleepiness, a decrease in pain sensation and (potentially) dysphoria, paranoia, and hallucinations. It also causes an increase in urine production because it inhibits the release of vasopressin. (Vasopressin is an endogenous substance that assists in regulating fluid and electrolyte balance in the body and decreases the amount of water released into the urine.) Unlike other opioids, substances that only bind to the κ receptor theoretically do not depress the respiratory system. The crystal structure of ketazocine was determined in 1983. (en) La chetazocina (INN), anche nota come chetociclazocina, è un derivato del benzomorfano utilizzato nella ricerca sui recettori oppioidi. La chetociclazocina è un oppioide esogeno che lega i recettori κ-oppioidi. L'attivazione di questo recettore è noto per causare sonnolenza, una riduzione della percezione del dolore e (potenzialmente) anche disforia, paranoia e allucinazioni. È anche causa di un aumento nella produzione urinaria in quanto inibisce il rilascio di vasopressina (è una sostanza endogena che coadiuva la regolazione del bilanciamento elettrolitico e dei fluidi nel corpo umano modulando la quantità di acqua rilasciata con le urine). (it)
prov:wasDerivedFrom	wikipedia-en:Ketazocine?oldid=1113856705&ns=0
page length (characters) of wiki page	3091 (xsd:nonNegativeInteger)
CAS number	36292-69-0
FDA UNII code	6IO4IG518S
KEGG	D04649
PubChem	3054741
foaf:isPrimaryTopicOf	wikipedia-en:Ketazocine
is Link from a Wikipage to another Wikipage of	Benzomorphan List of opioids C18H23NO2 Psychotomimetism Spiradoline Opioid Ethylketazocine Κ-opioid receptor

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