Leslie Stephen Coles (January 19, 1941 – December 3, 2014) was an American biogerontologist who was the co-founder and executive director of the Gerontology Research Group where he conducted research on supercentenarians and on aging. He was also a visiting scholar in the computer science department at the University of California, Los Angeles and an assistant researcher in the Department of Surgery, at the David Geffen School of Medicine.