The Spider-Slayers are a group of robots that appear in the comic books published by Marvel Comics. Created by Stan Lee and Steve Ditko, the original Spider-Slayer first appeared in The Amazing Spider-Man #25 (June 1965). Primarily foes of Spider-Man, the first Spider-Slayer was built by scientist Spencer Smythe who created several more of the robots to combat the hero up until his death. Afterwards, several others made Spider-Slayers, including Alistair Alphonso Smythe.