Lou Nelle Sutton (December 20, 1905 – July 1, 1994) was a businesswoman and former state representative from San Antonio, Texas. Born Lou Nelle Callahan, she married Garlington "G. J." Sutton in 1958. Together they would raise his daughter Jeffrey Dean Sutton. With the encouragement of her husband's best friend Claude Black, Sutton ran and succeeded her late husband in the Texas House of Representatives She represented her district from 1976-1987.