María Pérez Marcano (born April 1, 1989) is a Puerto Rican judoka. She competed at the 2016 Summer Olympics in Rio de Janeiro, in the women's 70 kg. She also competed in the women's 70 kg event at the 2020 Summer Olympics in Tokyo, Japan. In 2020, she won the silver medal in the women's 70 kg event at the 2020 Pan American Judo Championships held in Guadalajara, Mexico.