A marker vaccine is a vaccine which allows for immunological differentiation (or segregation) of infected from vaccinated animals, and is also referred to as a DIVA (or SIVA) vaccine [Differentiation (or Segregation) of infected from vaccinated animals] in veterinary medicine. In practical terms, this is most often achieved by omitting an immunogenic antigen present in the pathogen being vaccinated against, thus creating a of vaccination. In contrast, vaccination with traditional vaccines containing the complete pathogen, either attenuated or inactivated, precludes the use of serology (e.g. analysis of specific antibodies in body fluids) in epidemiological surveys in vaccinated populations.
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| - Markerová vakcína (cs)
- Markerimpfstoff (de)
- Marker vaccine (en)
- DIVA-vaccin (nl)
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| - Markerová vakcína (marker vaccine) je značená vakcína. Po její aplikaci dokážeme odlišit protilátky postvakcinační od protilátek po prodělané nemoci. V anglicky mluvících zemích se všechny vakcíny na tomto principu označují jako DIVA (Differentiating Infected from Vaccinated Animals). (cs)
- Ein Markerimpfstoff oder eine Markervakzine (auch: DIVA-Impfstoff oder -Vakzine) ist ein Tierimpfstoff, der es erlaubt, geimpfte von infizierten Tieren zu unterscheiden. (de)
- Een DIVA-vaccin (“Differentiating Infected from Vaccinated Animals”) is een speciaal soort vaccin, waardoor het mogelijk is onderscheid te maken tussen geïnfecteerde en gevaccineerde dieren. (nl)
- A marker vaccine is a vaccine which allows for immunological differentiation (or segregation) of infected from vaccinated animals, and is also referred to as a DIVA (or SIVA) vaccine [Differentiation (or Segregation) of infected from vaccinated animals] in veterinary medicine. In practical terms, this is most often achieved by omitting an immunogenic antigen present in the pathogen being vaccinated against, thus creating a of vaccination. In contrast, vaccination with traditional vaccines containing the complete pathogen, either attenuated or inactivated, precludes the use of serology (e.g. analysis of specific antibodies in body fluids) in epidemiological surveys in vaccinated populations. (en)
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| - Markerová vakcína (marker vaccine) je značená vakcína. Po její aplikaci dokážeme odlišit protilátky postvakcinační od protilátek po prodělané nemoci. V anglicky mluvících zemích se všechny vakcíny na tomto principu označují jako DIVA (Differentiating Infected from Vaccinated Animals). (cs)
- Ein Markerimpfstoff oder eine Markervakzine (auch: DIVA-Impfstoff oder -Vakzine) ist ein Tierimpfstoff, der es erlaubt, geimpfte von infizierten Tieren zu unterscheiden. (de)
- A marker vaccine is a vaccine which allows for immunological differentiation (or segregation) of infected from vaccinated animals, and is also referred to as a DIVA (or SIVA) vaccine [Differentiation (or Segregation) of infected from vaccinated animals] in veterinary medicine. In practical terms, this is most often achieved by omitting an immunogenic antigen present in the pathogen being vaccinated against, thus creating a of vaccination. In contrast, vaccination with traditional vaccines containing the complete pathogen, either attenuated or inactivated, precludes the use of serology (e.g. analysis of specific antibodies in body fluids) in epidemiological surveys in vaccinated populations. Apart from the obvious advantage of allowing continued serological monitoring of vaccinated individuals, cohorts or populations; the serological difference between vaccinated individuals and individuals that were exposed to the pathogen, and were contagious, can be used to continuously monitor the efficacy and safety of the vaccine. (en)
- Een DIVA-vaccin (“Differentiating Infected from Vaccinated Animals”) is een speciaal soort vaccin, waardoor het mogelijk is onderscheid te maken tussen geïnfecteerde en gevaccineerde dieren. (nl)
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