About: Matrix-assisted laser desorption electrospray ionization

Facets (new session)
Description
Metadata
Settings
- Rule:
- Inverse Functional Properties:
- "Same As":

About: Matrix-assisted laser desorption electrospray ionization Goto Sponge NotDistinct Permalink

An Entity of Type : dbo:TopicalConcept, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
QRcode icon

http://dbpedia.demo.openlinksw.com/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FMatrix-assisted_laser_desorption_electrospray_ionization

Matrix-assisted laser desorption electrospray ionization (MALDESI) was first introduced in 2006 as a novel ambient ionization technique which combines the benefits of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). An infrared (IR) or ultraviolet (UV) laser can be utilized in MALDESI to resonantly excite an endogenous or exogenous matrix. The term ‘matrix’ refers to any molecule that is present in large excess and absorbs the energy of the laser, thus facilitating desorption of analyte molecules. The original MALDESI design was implemented using common organic matrices, similar to those used in MALDI, along with a UV laser. The current MALDESI source employs endogenous water or a thin layer of exogenously deposited ice as the energy-absorbing matrix w

Attributes	Values
rdf:type	topical concept
rdfs:label	Matrix-assisted laser desorption electrospray ionization (en)
rdfs:comment	Matrix-assisted laser desorption electrospray ionization (MALDESI) was first introduced in 2006 as a novel ambient ionization technique which combines the benefits of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). An infrared (IR) or ultraviolet (UV) laser can be utilized in MALDESI to resonantly excite an endogenous or exogenous matrix. The term ‘matrix’ refers to any molecule that is present in large excess and absorbs the energy of the laser, thus facilitating desorption of analyte molecules. The original MALDESI design was implemented using common organic matrices, similar to those used in MALDI, along with a UV laser. The current MALDESI source employs endogenous water or a thin layer of exogenously deposited ice as the energy-absorbing matrix w (en)
foaf:depiction
dcterms:subject	Ion source
Wikipage page ID	18266330 (xsd:integer)
Wikipage revision ID	1083140368 (xsd:integer)
Link from a Wikipage to another Wikipage	Electrospray ionization Metabolomics Desorption Arabidopsis Peptide Desorption atmospheric pressure photoionization Infrared Neurotransmitter Mass-to-charge ratio Mass spectrometry data format Quadrupole mass analyzer MATLAB Matrix-assisted laser desorption/ionization HIV HeLa Ion-mobility spectrometry–mass spectrometry Laser ablation electrospray ionization Lipid Ambient ionization Fourier transform Chromatography Glycan Principal component analysis Region of interest dbr:Tetrabromobisphenol_A Ion source Laser Biomolecule Textile Auxin Fiber dbr:Indole-3-acetic_acid Mass spectrometry imaging Matrix (mass spectrometry) Ultraviolet Excited state Flame retardant Management of HIV/AIDS Orbitrap
Link from a Wikipage to an external page	https://msireader.wordpress.ncsu.edu/
sameAs	Matrix-assisted laser desorption electrospray ionization Matrix-assisted laser desorption electrospray ionization Matrix-assisted laser desorption electrospray ionization Matrix-assisted laser desorption electrospray ionization Matrix-assisted laser desorption electrospray ionization
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Mass_spectrometry
thumbnail	wiki-commons:Special:FilePath/IR-MALDESI_Imaging_Schematic.png?width=300
has abstract	Matrix-assisted laser desorption electrospray ionization (MALDESI) was first introduced in 2006 as a novel ambient ionization technique which combines the benefits of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). An infrared (IR) or ultraviolet (UV) laser can be utilized in MALDESI to resonantly excite an endogenous or exogenous matrix. The term ‘matrix’ refers to any molecule that is present in large excess and absorbs the energy of the laser, thus facilitating desorption of analyte molecules. The original MALDESI design was implemented using common organic matrices, similar to those used in MALDI, along with a UV laser. The current MALDESI source employs endogenous water or a thin layer of exogenously deposited ice as the energy-absorbing matrix where O-H symmetric and asymmetric stretching bonds are resonantly excited by a mid-IR laser. The IR-MALDESI source can be used for mass spectrometry imaging (MSI), a technique using MS data analyzed from a sample area to detect hundreds to thousands of biomolecules and visualize their spatial distributions. The IR-MALDESI MSI source was designed and implemented in 2013, and is coupled to a high resolving power hybrid Quadrupole-Orbitrap mass spectrometer. The computer controlled motorized stage and a charge-coupled device (CCD) camera are placed in a nitrogen purged enclosure where ambient ions and relative humidity can be regulated. A water-cooled Peltier thermoelectric plate is used to control the sample stage temperature (−10 °C to 80 °C). The source has single- or multi-shot capabilities with adjustable laser fluence, repetition rate, and delay between the laser trigger and MS ion accumulation. Over the past ten years, transformative developments in the laser technology, data acquisition, motor-control software (RastirX), and imaging processing software (MSiReader) have promoted IR-MALDESI as a powerful tool for the direct analysis and MSI of diverse biological, forensic, and pharmaceutical samples. (en)
gold:hypernym	Technique
prov:wasDerivedFrom	wikipedia-en:Matrix-assisted_laser_desorption_electrospray_ionization?oldid=1083140368&ns=0
page length (characters) of wiki page	33426 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Matrix-assisted_laser_desorption_electrospray_ionization
is Link from a Wikipage to another Wikipage of	Electrospray ionization Desorption electrospray ionization List of mass spectrometry acronyms Ion source Laser ablation electrospray ionization Ambient ionization
is foaf:primaryTopic of	wikipedia-en:Matrix-assisted_laser_desorption_electrospray_ionization

Faceted Search & Find service v1.17_git139 as of Feb 29 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (378 GB total memory, 59 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software