Mercy High School, San Francisco was a Catholic all-girls college-preparatory high school located in San Francisco, California. It was a part of the Roman Catholic Archdiocese of San Francisco, and was sponsored by the Sisters of Mercy in Dublin, Ireland. The campus was located on 19th Avenue, near San Francisco State University, and included a multipurpose pavilion, which was built and dedicated to Catherine McAuley in 2001. The school permanently closed in the summer of 2020.