Merle Karusoo (born 1 July 1944 in Rae Parish) is an Estonian stage director and writer. She is also known as a collector of Estonian biographies. In 1972, she graduated from University of Tartu in Estonian philology. In 1999, she defended her master's thesis in sociology at Tallinn Pedagogical University. She has worked as a director at the Estonian Drama Theatre and the Estonian State Youth Theater.