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About: Neuropeptide S receptor     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:Thing100002452, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: ThingpersonBiomoleculegeneBiomoleculeGeneyago:BodyPart105220461yago:Part109385911yago:PhysicalEntity100001930yago:Receptor105608868yago:WikicatGProteinCoupledReceptorsHumanGeneyago:Structure105225602yago:Thing100002452 New Facet based on Instances of this Class

The neuropeptide S receptor (NPSR) is a member of the G-protein coupled receptor superfamily of integral membrane proteins which binds neuropeptide S (NPS). It was formerly an orphan receptor, GPR154, until the discovery of neuropeptide S as the endogenous ligand. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. This gene is a member of the G protein-coupled receptor 1 family and encodes a plasma membrane protein. Mutations in this gene have also been associated with this disease.