New York State Route 100 (NY 100) is a major north–south state highway in Westchester County, New York, in the United States. It begins parallel to Interstate 87 (I-87) at a junction with the Cross County Parkway in the city of Yonkers and runs through most of the length of the county up to U.S. Route 202 (US 202) in the town of Somers. NY 100 was designated as part of the 1930 renumbering of state highways in New York. Prior to becoming a state road, various sections of NY 100 were part of several important early roads in the county.