Nicola Padoin (born 24 February 1979) is an Italian footballer who plays as a midfielder for Foligno. Padoin left for Empoli F.C. in co-ownership deal in 1999 from A.C. Milan. He played two games in the 2002–03 Serie A for Empoli F.C. In the 2006–07 Serie B his dramatic winning goal in the 91st minute of the last regular season game against Juventus F.C. saved Spezia Calcio from relegation.