Nyaicili Boki Raja (died after 1556) was a Queen of Ternate in Maluku Islands who served as regent of the kingdom in 1545-1546. She was later baptized by the Catholic missionary Francis Xavier and took the name Dona Isabel. Being the daughter, wife, sister and mother of kings, she had a potentially bridge-building function between the competing Malukan spice Sultanates Ternate and Tidore, but was repeatedly sidelined by the brutal policy of early European colonialism in Maluku.
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