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OrthoDB presents a catalog of orthologous protein-coding genes across vertebrates, arthropods, fungi, plants, and bacteria. Orthology refers to the last common ancestor of the species under consideration, and thus OrthoDB explicitly delineates orthologs at each major radiation along the species phylogeny. The database of orthologs presents available protein descriptors, together with Gene Ontology and InterPro attributes, which serve to provide general descriptive annotations of the orthologous groups, and facilitate comprehensive orthology database querying. OrthoDB also provides computed evolutionary traits of orthologs, such as gene duplicability and loss profiles, divergence rates, sibling groups, and gene intron-exon architectures.

Attributes	Values
rdf:type	Thing schema:CreativeWork work wikidata:Q386724 Database dul:InformationObject Biological database
rdfs:label	OrthoDB (fr) OrthoDB (en)
rdfs:comment	OrthoDB est un catalogue de gènes codant des protéines orthologues à travers les vertébrés, les arthropodes, les fungi, et les bactéries. L'orthologie fait référence au dernier ancêtre commun d'un ensemble d'espèces considérées, et donc OrthoDB définie explicitement les orthologues à chaque point de rayonnement le long de la phylogénie des espèces. La base de données OrthoDB fourni des descripteurs de protéines, ainsi que les attributs GO et InterPro, qui servent à fournir des annotations descriptives générales des groupes orthologues et faciliter l'interrogation de base de données de orthologie. OrthoDB fournit également des traits évolutifs d'orthologues calculés, comme les duplications et les profils de perte, les taux de divergence, et des familles, qui sont maintenant étendus pour inc (fr) OrthoDB presents a catalog of orthologous protein-coding genes across vertebrates, arthropods, fungi, plants, and bacteria. Orthology refers to the last common ancestor of the species under consideration, and thus OrthoDB explicitly delineates orthologs at each major radiation along the species phylogeny. The database of orthologs presents available protein descriptors, together with Gene Ontology and InterPro attributes, which serve to provide general descriptive annotations of the orthologous groups, and facilitate comprehensive orthology database querying. OrthoDB also provides computed evolutionary traits of orthologs, such as gene duplicability and loss profiles, divergence rates, sibling groups, and gene intron-exon architectures. (en)
foaf:homepage	https://www.orthodb.org/
foaf:depiction
dc:description	Catalog ofOrthologs.
dct:subject	Biological databases Evolutionary biology Phylogenetics
Wikipage page ID	31367370 (xsd:integer)
Wikipage revision ID	1091105494 (xsd:integer)
Link from a Wikipage to another Wikipage	List of biological databases UniProt Fungi Gene Ontology Comparative genomics Bacteria Biological databases FlyBase Ensembl Arthropods Evolutionary biology Phylogenetics Swiss Institute of Bioinformatics Homology (biology) Phylogeny Plants InterPro National Center for Biotechnology Information Sequence homology Smith–Waterman algorithm Vertebrates Orthologs
Link from a Wikipage to an external page	http://busco.ezlab.org/ https://sparql.orthodb.org/sparql http://www.orthodb.org https://scholar.google.ch/citations%3Fuser=6u3YZkUAAAAJ https://www.orthodb.org/ https://www.orthodb.org/%3Fpage=filelist https://creativecommons.org/licenses/by/3.0/%7CCC-BY-3.0 https://www.ncbi.nlm.nih.gov/sites/entrez%3Fdb=pubmed&cmd=link&LinkName=pubmed_pubmed_citedin&from_uid=17947323
sameAs	OrthoDB OrthoDB OrthoDB OrthoDB
sparql	https://sparql.orthodb.org/sparql
dbp:wikiPageUsesTemplate	dbt:Infobox_biodatabase dbt:Reflist
thumbnail	wiki-commons:Special:FilePath/OrthoDB_logo.png?width=300
author	Evgenia V. Kriventseva (en)
citation	Kriventseva et al. (en)
description	Catalog of Orthologs. (en)
license	https://creativecommons.org/licenses/by/3.0/%7CCC-BY-3.0
logo	150 (xsd:integer)
released	2007 (xsd:integer)
title	OrthoDB (en)
url	https://www.orthodb.org/
Center	Swiss Institute of Bioinformatics
has abstract	OrthoDB est un catalogue de gènes codant des protéines orthologues à travers les vertébrés, les arthropodes, les fungi, et les bactéries. L'orthologie fait référence au dernier ancêtre commun d'un ensemble d'espèces considérées, et donc OrthoDB définie explicitement les orthologues à chaque point de rayonnement le long de la phylogénie des espèces. La base de données OrthoDB fourni des descripteurs de protéines, ainsi que les attributs GO et InterPro, qui servent à fournir des annotations descriptives générales des groupes orthologues et faciliter l'interrogation de base de données de orthologie. OrthoDB fournit également des traits évolutifs d'orthologues calculés, comme les duplications et les profils de perte, les taux de divergence, et des familles, qui sont maintenant étendus pour inclure les détails d'architecture d'intron-exon, orthologues de synténie, et les arbres parent-enfant. (fr) OrthoDB presents a catalog of orthologous protein-coding genes across vertebrates, arthropods, fungi, plants, and bacteria. Orthology refers to the last common ancestor of the species under consideration, and thus OrthoDB explicitly delineates orthologs at each major radiation along the species phylogeny. The database of orthologs presents available protein descriptors, together with Gene Ontology and InterPro attributes, which serve to provide general descriptive annotations of the orthologous groups, and facilitate comprehensive orthology database querying. OrthoDB also provides computed evolutionary traits of orthologs, such as gene duplicability and loss profiles, divergence rates, sibling groups, and gene intron-exon architectures. In comparative genomics, the importance of scale cannot be underestimated. As gene orthology delineation requires specific expertise and considerable computational resources, scale is something that individual non-specialist research groups cannot accomplish on their own. This challenging task is achieved by OrthoDB, with very comprehensive sets of species and several unique features such as the extensive functional and evolutionary annotations of orthologous groups, with the integration of many useful links to other world-leading databases that focus on capturing information about gene function. No genome can exist as a useful data source without extensive comparative analyses with other genomes – OrthoDB provides a critically important resource for comparative genomics for the entire community of researchers from those interested in grand evolutionary questions to those focused on the specific biological functions of individual genes. (en)
download	https://www.orthodb.org/%3Fpage=filelist
laboratory	Computational Evolutionary Genomics Group (en)
prov:wasDerivedFrom	wikipedia-en:OrthoDB?oldid=1091105494&ns=0
page length (characters) of wiki page	13423 (xsd:nonNegativeInteger)
title	OrthoDB (en)
foaf:isPrimaryTopicOf	wikipedia-en:OrthoDB
is Link from a Wikipage to another Wikipage of	Infologs TreeFam Swiss Institute of Bioinformatics Orthologous MAtrix Sequence homology Phylogenetic inference using transcriptomic data
is foaf:primaryTopic of	wikipedia-en:OrthoDB

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