Patricia Donoho Hughes (August 18, 1930 – January 20, 2010) was a First Lady of Maryland, married to former Maryland Governor Harry Hughes. She was educated at Sorbonne (1949) and Bryn Mawr College (1951). She and Hughes eloped on February 7, 1950, and got a marriage licence in Prince George's county before officially getting married on June 30, 1951. She later continued her education at the University of Delaware (1966). Mrs. Hughes was a teacher and educator by profession. While serving as first lady in the 1980s, she worked to restore Government House, the governor's mansion.