Peter Guy Wolynes is an American theoretical chemist and physicist. Since 2011 he has been a Bullard-Welch Foundation Professor of Science and Professor of Chemistry at Rice University. He is widely recognized for his significant contributions to the theories of protein folding, glasses, and gene networks. Previously he was James R. Eiszner Professor at the University of Illinois at Urbana-Champaign, and the Francis H.C. Crick Chair of Physical Sciences at the University of California, San Diego.