About: Pralmorelin

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Pralmorelin (INN) (brand name GHRP Kaken 100; former developmental code names KP-102, GPA-748, WAY-GPA-748), also known as pralmorelin hydrochloride (JAN) and pralmorelin dihydrochloride (USAN), as well as, notably, growth hormone-releasing peptide 2 (GHRP-2), is a growth hormone secretagogue (GHS) used as a diagnostic agent that is marketed by in Japan in a single-dose formulation for the assessment of growth hormone deficiency (GHD).

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug drug
rdfs:label	Pralmorelin (en)
rdfs:comment	Pralmorelin (INN) (brand name GHRP Kaken 100; former developmental code names KP-102, GPA-748, WAY-GPA-748), also known as pralmorelin hydrochloride (JAN) and pralmorelin dihydrochloride (USAN), as well as, notably, growth hormone-releasing peptide 2 (GHRP-2), is a growth hormone secretagogue (GHS) used as a diagnostic agent that is marketed by in Japan in a single-dose formulation for the assessment of growth hormone deficiency (GHD). (en)
foaf:depiction
dcterms:subject	Abandoned drugs World Anti-Doping Agency prohibited substances Growth hormone secretagogues Ghrelin receptor agonists Peptides
Wikipage page ID	46946727 (xsd:integer)
Wikipage revision ID	1003125790 (xsd:integer)
Link from a Wikipage to another Wikipage	Blood plasma Peptide Structural analog List of growth hormone secretagogues Abandoned drugs World Anti-Doping Agency prohibited substances Growth hormone secretagogues Oral administration Organic compound Clinical trial Ghrelin receptor agonists Drug Japanese Accepted Name Agonist International Nonproprietary Name Japan Hunger Peptides Growth hormone Growth hormone deficiency Growth hormone secretagogue Growth hormone secretagogue receptor dbr:Met-enkephalin Short stature United States Adopted Name Phases of clinical research Diagnostic agent Amino acid sequence Food intake Pituitary dwarfism dbr:%3C/nowiki%3E(2''S'')-2-%3Cnowiki%3E%5B%5B%3C/nowiki%3E(2''S'')-2-%3Cnowiki%3E%5B%5B%3C/nowiki%3E(2''S'')-2-%3Cnowiki%3E%5B%5B%3C/nowiki%3E(2''R'')-2-%3Cnowiki%3E%5B%5B%3C/nowiki%3E(2''R'')-2-aminopropanoyl%5Damino%5D-3-naphthalen-2-ylpropanoyl%5Damino%5Dpropanoyl%5Damino%5D-3-(1''H''-indol-3-yl)propanoyl%5Damino%5D-3-phenylpropanoyl%5Damino%5Dhexanamide dbr:Kaken_Pharmaceutical
sameAs	Pralmorelin Pralmorelin Pralmorelin Pralmorelin Pralmorelin
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Fdacite dbt:Diagnostic_agents dbt:Systemic-hormonal-drug-stub dbt:GH/IGF-1_axis_signaling_modulators
thumbnail	wiki-commons:Special:FilePath/Pralmorelin.svg?width=300
c	45 (xsd:integer)
CAS number	158861 (xsd:integer)
ChemSpiderID	5293451 (xsd:integer)
H	55 (xsd:integer)
IUPAC name	-6 (xsd:integer)
n	9 (xsd:integer)
O	6 (xsd:integer)
PubChem	6852372 (xsd:integer)
routes of administration	Oral, intravenous (en)
SMILES	C[C@H]N (en)
StdInChI	1 (xsd:integer)
StdInChIKey	HRNLPPBUBKMZMT-RDRUQFPZSA-N (en)
synonyms	D-Alanyl-3--D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide (en)
UNII	E6S6E1F19M (en)
width	250 (xsd:integer)
has abstract	Pralmorelin (INN) (brand name GHRP Kaken 100; former developmental code names KP-102, GPA-748, WAY-GPA-748), also known as pralmorelin hydrochloride (JAN) and pralmorelin dihydrochloride (USAN), as well as, notably, growth hormone-releasing peptide 2 (GHRP-2), is a growth hormone secretagogue (GHS) used as a diagnostic agent that is marketed by in Japan in a single-dose formulation for the assessment of growth hormone deficiency (GHD). Pralmorelin is an orally-active, synthetic peptide drug, specifically, an analogue of met-enkephalin, with the amino acid sequence D-Ala-D-(β-naphthyl)-Ala-Trp-D-Phe-Lys-NH2. It acts as a ghrelin/growth hormone secretagogue receptor (GHSR) agonist, and was the first of this class of drugs to be introduced clinically. Acute administration of the drug markedly increases the levels of plasma growth hormone (GH) and reliably induces sensations of hunger and increases food intake in humans. Pralmorelin was also under investigation for the treatment of GHD and short stature (pituitary dwarfism), and made it to phase II clinical trials for these indications, but was ultimately never marketed for them. This may be because the ability of pralmorelin to increase plasma GH levels is significantly lower in people with GHD relative to healthy individuals. (en)
IUPHAR ligand	1092 (xsd:integer)
gold:hypernym	Secretagogue
prov:wasDerivedFrom	wikipedia-en:Pralmorelin?oldid=1003125790&ns=0
page length (characters) of wiki page	7784 (xsd:nonNegativeInteger)
CAS number	158861-67-7
FDA UNII code	E6S6E1F19M
PubChem	6852372
foaf:isPrimaryTopicOf	wikipedia-en:Pralmorelin
is Link from a Wikipage to another Wikipage of	Appetite stimulant Josh Ravin List of Major League Baseball players suspended for performance-enhancing drugs List of people banned or suspended by the NBA Doping at the Olympic Games 2019 Boston Red Sox season 2020 in UFC Steven Wright (baseball) CCC Pro Team 2021 in UFC 2022 in UFC Examorelin 2015 Pan American Games Ipamorelin John Collins (basketball) Sona Poghosyan

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