Priscilla Hiss (October 13, 1903 – October 14, 1984), born Priscilla Fansler and first married as Priscilla Hobson, was a 20th-century American teacher and book editor, best known as the wife of Alger Hiss, an alleged Communist and former State Department official whose innocence she supported with testimony throughout his two, highly publicized criminal trials in 1949.