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Rolitetracycline is a tetracycline antibiotic. Tetracycline is N-Mannich base prodrug that is prepared from tetracycline by condensation with pyrrolidine and formaldehyde to produce rolitetracycline. Rolitetracycline is used as an antibacterial drug, a protein synthesis inhibitor, an antiprotozoal drug and a prodrug.

AttributesValues
rdf:type
rdfs:label
  • Rolitetraciclina (it)
  • Rolitetracycline (en)
rdfs:comment
  • Rolitetracycline is a tetracycline antibiotic. Tetracycline is N-Mannich base prodrug that is prepared from tetracycline by condensation with pyrrolidine and formaldehyde to produce rolitetracycline. Rolitetracycline is used as an antibacterial drug, a protein synthesis inhibitor, an antiprotozoal drug and a prodrug. (en)
  • La rolitetraciclina è un antibiotico facente parte del gruppo delle tetracicline. Si tratta di un profarmaco, derivato della tetraciclina dalla quale è ottenuto per condensazione con pirrolidina e formaldeide a dare la relativa base di Mannich. Tale modifica è funzionale ad aumentare l'idrofilia del composto per renderlo solubile in acqua e permetterne la somministrazione endovenosa. (it)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/Rolitetracycline.svg
  • http://commons.wikimedia.org/wiki/Special:FilePath/Rolitetracycline_3D_spacefill.png
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
sameAs
dbp:wikiPageUsesTemplate
thumbnail
ATC suffix
  • AA09 (en)
alt
  • Skeletal formula of rolitetracycline (en)
  • Space-filling model of the rolitetracycline molecule (en)
ATC prefix
  • J01 (en)
c
CAS number
ChEMBL
ChemSpiderID
DrugBank
  • DB01301 (en)
H
image
  • Rolitetracycline 3D spacefill.png (en)
IUPAC name
KEGG
  • D02282 (en)
n
O
PubChem
SMILES
  • O=C\C2=C[C@@H][C@@H]3CC5C\Cc4ccccc4[C@@]5O (en)
StdInChI
StdInChIKey
  • HMEYVGGHISAPJR-VQCPGFMQSA-N (en)
synonyms
  • (-4-Dimethylamino-6,10,11,12a-tetrahydroxy-2-[hydroxy-methylidene]-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione) (en)
UNII
  • GH9IW85221 (en)
Verifiedfields
  • changed (en)
verifiedrevid
Watchedfields
  • changed (en)
width
has abstract
  • Rolitetracycline is a tetracycline antibiotic. Tetracycline is N-Mannich base prodrug that is prepared from tetracycline by condensation with pyrrolidine and formaldehyde to produce rolitetracycline. Rolitetracycline is used as an antibacterial drug, a protein synthesis inhibitor, an antiprotozoal drug and a prodrug. (en)
  • La rolitetraciclina è un antibiotico facente parte del gruppo delle tetracicline. Si tratta di un profarmaco, derivato della tetraciclina dalla quale è ottenuto per condensazione con pirrolidina e formaldeide a dare la relativa base di Mannich. Tale modifica è funzionale ad aumentare l'idrofilia del composto per renderlo solubile in acqua e permetterne la somministrazione endovenosa. (it)
prov:wasDerivedFrom
page length (characters) of wiki page
CAS number
  • 751-97-3
ChEMBL
  • 1214184
DrugBank
  • DB01301
FDA UNII code
  • GH9IW85221
KEGG
  • D02282
PubChem
  • 54682938
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