The Diocese of Venafro was a Roman Catholic diocese in Italy, located in Venafro, province of Isernia, region of Molise in the ecclesiastical province of Capua. In 1852, the dioceses of Isernia and Venafro were united under the governance of one and the same bishop, aeque personaliter. The diocese of Venafro was premanently suppressed on 30 September 1986.