SM UC-64 was a German Type UC II minelaying submarine or U-boat in the German Imperial Navy (German: Kaiserliche Marine) during World War I. The U-boat was ordered on 12 January 1916, laid down on 3 April 1916, and was launched on 23 January 1917. She was commissioned into the German Imperial Navy on 22 February 1917 as SM UC-64. In 15 patrols UC-64 was credited with sinking 26 ships, either by torpedo or by mines laid. UC-64 was mined and sunk in the Dover Strait on 20 June 1918.