Samuel Lewis Casey (February 12, 1821 – August 25, 1902) was a U.S. Representative from Kentucky. Born near Caseyville, Kentucky, Casey attended the country schools. He engaged in mercantile pursuits. In 1853, President of the United States Franklin Pierce nominated Casey to be Treasurer of the United States. Casey held this office from April 4, 1853 to December 22, 1859. He served as member of the Kentucky House of Representatives from 1860 to 1862.