Sarah Achieng Opendi, sometimes Sarah Opendi Achieng, is a Ugandan accountant and politician. She is the State Minister of Mineral Development in the Ugandan cabinet, since 14 December 2019. Before that, from 6 June 2016 until 14 December 2019, she served as the State Minister of Health for General Duties. Prior to that, from 15 August 2012 until 6 June 2016, she served as the Minister of State for Primary Healthcare. Prior to that, from 27 May 2011 until 15 August 2012, she served as the State Minister for Lands. In the cabinet reshuffle of 1 March 2015, she retained her cabinet post.