Sophia Chan Siu-chee GBS JP (Chinese: 陳肇始; born 1958) is a Hong Kong professor and politician. She served as Secretary for Food and Health from 2017 to 2022. She was educated at the St. Paul's Secondary School. She subsequently graduated from the University of Manchester with a Master of Education, the Harvard University with a Master of Public Health and the University of Hong Kong with a Doctor of Philosophy Degree. She was a Professor in Nursing and Director of Research in HKU's School of Nursing and an Assistant Dean of the Li Ka Shing Faculty of Medicine of HKU.