Squash competitions at the 2022 Bolivarian Games in Valledupar, Colombia were held from 25 to 29 June 2022 at Unidad Deportiva El Salitre in Bogotá, a sub-venue outside Valledupar. Seven medal events were scheduled to be contested; singles, doubles and team events for men and women plus a mixed doubles event. A total of 45 athletes (23 men and 22 women) competed in the events. The events were open competitions without age restrictions. Colombia, who were the competition defending champions after Santa Marta 2017, won the squash competitions again after winning 6 of the 7 gold medals at stake