About: Suspension array technology

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Suspension array technology (or SAT) is a high throughput, large-scale, and multiplexed screening platform used in molecular biology. SAT has been widely applied to genomic and proteomic research, such as single nucleotide polymorphism (SNP) genotyping, genetic disease screening, gene expression profiling, screening drug discovery and clinical diagnosis. SAT uses microsphere beads (5.6 um in diameter) to prepare arrays. SAT allows for the simultaneous testing of multiple gene variants through the use of these microsphere beads as each type of microsphere bead has a unique identification based on variations in optical properties, most common is fluorescent colour. As each colour and intensity of colour has a unique wavelength, beads can easily be differentiated based on their wavelength int

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rdf:type	yago:WikicatMolecularBiologyTechniques yago:Ability105616246 yago:Abstraction100002137 yago:Cognition100023271 yago:Know-how105616786 yago:Method105660268 yago:PsychologicalFeature100023100 yago:Technique105665146
rdfs:label	Suspension array technology (en)
rdfs:comment	Suspension array technology (or SAT) is a high throughput, large-scale, and multiplexed screening platform used in molecular biology. SAT has been widely applied to genomic and proteomic research, such as single nucleotide polymorphism (SNP) genotyping, genetic disease screening, gene expression profiling, screening drug discovery and clinical diagnosis. SAT uses microsphere beads (5.6 um in diameter) to prepare arrays. SAT allows for the simultaneous testing of multiple gene variants through the use of these microsphere beads as each type of microsphere bead has a unique identification based on variations in optical properties, most common is fluorescent colour. As each colour and intensity of colour has a unique wavelength, beads can easily be differentiated based on their wavelength int (en)
foaf:depiction
dcterms:subject	Bioinformatics DNA Gene expression Microtechnology Molecular biology techniques Microarrays
Wikipage page ID	30990996 (xsd:integer)
Wikipage revision ID	1123484511 (xsd:integer)
Link from a Wikipage to another Wikipage	Proteins DNA DNA microarray Polymerase chain reaction Nucleic acid Bioinformatics DNA Complementarity (molecular biology) Gene expression Oligonucleotide Gene expression Microtechnology Molecular biology techniques Fluorescent Flow cytometry Microarrays Antibodies Genomic Molecular biology Proteomic Single nucleotide polymorphism Genetic disease
Link from a Wikipage to an external page	http://www.luminexcorp.com/
sameAs	Suspension array technology Suspension array technology Suspension array technology Suspension array technology
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thumbnail	wiki-commons:Special:FilePath/Suspension_array.jpg?width=300
has abstract	Suspension array technology (or SAT) is a high throughput, large-scale, and multiplexed screening platform used in molecular biology. SAT has been widely applied to genomic and proteomic research, such as single nucleotide polymorphism (SNP) genotyping, genetic disease screening, gene expression profiling, screening drug discovery and clinical diagnosis. SAT uses microsphere beads (5.6 um in diameter) to prepare arrays. SAT allows for the simultaneous testing of multiple gene variants through the use of these microsphere beads as each type of microsphere bead has a unique identification based on variations in optical properties, most common is fluorescent colour. As each colour and intensity of colour has a unique wavelength, beads can easily be differentiated based on their wavelength intensity. Microspheres are readily suspendable in solution and exhibit favorable kinetics during an assay. Similar to flat microarrays (e.g. DNA microarray), an appropriate receptor molecule, such as DNA oligonucleotide probes, antibodies, or other proteins, attach themselves to the differently labeled microspheres. This produces thousands of microsphere array elements. Probe-target hybridization is usually detected by optically labeled targets, which determines the relative abundance of each target in the sample. (en)
gold:hypernym	Throughput
prov:wasDerivedFrom	wikipedia-en:Suspension_array_technology?oldid=1123484511&ns=0
page length (characters) of wiki page	9109 (xsd:nonNegativeInteger)
foaf:isPrimaryTopicOf	wikipedia-en:Suspension_array_technology
is Link from a Wikipage to another Wikipage of	Single-nucleotide polymorphism
is foaf:primaryTopic of	wikipedia-en:Suspension_array_technology

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