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About: TRAMP complex     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : yago:WikicatProteinComplexes, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)

Type: yago:Abstraction100002137yago:Cognition100023271yago:Complex105870365yago:Concept105835747yago:Content105809192yago:Idea105833840yago:PsychologicalFeature100023100yago:Whole105869584yago:WikicatProteinComplexes New Facet based on Instances of this Class

TRAMP complex (Trf4/Air2/Mtr4p Polyadenylation complex) is a multiprotein, heterotrimeric complex having distributive polyadenylation activity and identifies wide varieties of RNAs produced by polymerases. It was originally discovered in Saccharomyces cerevisiae by LaCava et al., Vanacova et al. and Wyers et al. in 2005. In this way, TRAMP plays a critical role in ridding the cell of noncoding transcripts generated through pervasive RNA polymerase II transcription, as well as functioning in the biogenesis and turnover of functional coding and noncoding RNAs.