The UAAP Season 80 seniors division football tournament started on February 3, 2018, with the women's tournament at the Rizal Memorial Stadium in Manila. While the juniors' division started on November 20, 2017 at the PFF National Training Centre inside the San Lazaro Leisure Park in Carmona, Cavite. National University Bullpups made their debut in the juniors' division. In the finals of the juniors' division, FEU Diliman successfully defended their crown for a record of eight consecutive titles after defeating De La Salle Zobel on penalties, 4–2.