Uncle Tom's Cabin is a 1910 American silent short drama produced by the Thanhouser Company. The film was adapted by from the 1852 novel Uncle Tom's Cabin by Harriet Beecher Stowe. The plot of the Thanhouser production streamlined the actual story to portray the film over the course of a single reel. The film was released on July 26, 1910, on the same day that Vitagraph released the first reel of their own three reel version of . This prompted the Thanhouser Company to advertise against the Vitagraph film by referring to the other as being overly drawn out. The film garnered mixed, but mostly positive reception in trade publications. The film is presumed lost.