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Vacuolar-type ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms. V-ATPases acidify a wide array of intracellular organelles and pumps protons across the plasma membranes of numerous cell types. V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular and plasma membranes of eukaryotic cells. It is generally seen as the polar opposite of ATP synthase because ATP synthase is a proton channel that uses the energy from a proton gradient to produce ATP. V-ATPase however, is a proton pump that uses the energy from ATP hydrolysis to produce a proton gradient.

AttributesValues
rdf:type
rdfs:label
  • V-ATPáza (cs)
  • V-ATPase (fr)
  • V형 ATP가수분해효소 (ko)
  • V-ATPase (pt)
  • V-ATPase (en)
rdfs:comment
  • V-ATPáza (V1-VO ATPáza či též vakuolární H+-ATPáza) je ATPázová pumpa vyskytující se v buňkách všech eukaryotických organismů. Přenáší protony ("vodíkové kationty") přes buněčné membrány dovnitř různých vnitrobuněčných váčků či přes cytoplazmatickou membránu, čímž je okyseluje. Patří mezi protonové pumpy. (cs)
  • A V-ATPase ou ATPase vacuolar ou ATPase H+ de tipo vacuolar é uma enzima antigo e muito conservada evolutivamente que desempenha funções muito diversas nos organismos eucarióticos. A V-ATPase acidifica vários organelos celulares e bombeia protões através da membrana plasmática de numerosos tipos celulares. As V-ATPases acoplam a energia da com transporte de protões através de membranas intracelulares e da membrana plasmática das células eucarióticas. (pt)
  • La V-ATPase est une hydrolase qui catalyse la réaction : ATP + H2O + H+intérieur ADP + phosphate + H+extérieur. Ces enzymes hautement conservées à travers l'évolution assurent des fonctions remarquablement diversifiées chez les eucaryotes. Elles acidifient un grand nombre d'organites intracellulaires et pompent les protons à travers la membrane plasmique de nombreux types de cellules. Elles réalisent cela en hydrolysant l'ATP pour libérer l'énergie nécessaire au transport actif des protons à travers les membranes cellulaires. (fr)
  • Vacuolar-type ATPase (V-ATPase) is a highly conserved evolutionarily ancient enzyme with remarkably diverse functions in eukaryotic organisms. V-ATPases acidify a wide array of intracellular organelles and pumps protons across the plasma membranes of numerous cell types. V-ATPases couple the energy of ATP hydrolysis to proton transport across intracellular and plasma membranes of eukaryotic cells. It is generally seen as the polar opposite of ATP synthase because ATP synthase is a proton channel that uses the energy from a proton gradient to produce ATP. V-ATPase however, is a proton pump that uses the energy from ATP hydrolysis to produce a proton gradient. (en)
name
  • V-ATPase, subunit C (en)
  • V-ATPase, subunit E (en)
  • V-ATPase, subunit G (en)
  • V-ATPase, subunit H, N-terminal (en)
  • V-ATPase, subunit I/a (en)
  • V-ATPase, subunit c (en)
  • V-ATPase, subunit d/d2 (en)
foaf:depiction
  • http://commons.wikimedia.org/wiki/Special:FilePath/VATPase-en.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/2bl2.png
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1ho8_EBI.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1r5z_EBI.jpg
  • http://commons.wikimedia.org/wiki/Special:FilePath/PDB_1u7l_EBI.jpg
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