There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach.
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rdf:type
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rdfs:label
| - Vasoactive intestinal peptide receptor (en)
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rdfs:comment
| - There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. (en)
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foaf:name
| - vasoactive intestinal peptide receptor 1 (en)
- vasoactive intestinal peptide receptor 2 (en)
- adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (en)
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name
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dct:subject
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Wikipage page ID
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Wikipage revision ID
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Link from a Wikipage to another Wikipage
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Link from a Wikipage to an external page
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sameAs
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dbp:wikiPageUsesTemplate
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OMIM
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AltSymbols
| - PACAPR (en)
- RDC1, HVR1, VAPC1 (en)
- VPAC2 (en)
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symbol
| - ADCYAP1R1 (en)
- VIPR1 (en)
- VIPR2 (en)
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UniProt
| - P32241 (en)
- P41586 (en)
- P41587 (en)
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has abstract
| - There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors are activated by the endogenous peptides VIP, PACAP-38, PACAP-27, peptide histidine isoleucineamide (PHI), peptide histidine methionineamide (PHM) and peptide histidine valine (PHV). “PACAP type II receptors” (VPAC1 and VPAC2 receptors) display comparable affinity for PACAP and VIP, whereas PACAP-27 and PACAP-38 are >100 fold more potent than VIP as agonists of most isoforms of the PAC1 receptor. (en)
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Arm
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band
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Chromosome
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EntrezGene
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HGNCid
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RefSeq
| - NM_001118 (en)
- NM_003382 (en)
- NM_004624 (en)
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gold:hypernym
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arm
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band
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chromosome
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EntrezGene
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HGNCid
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