About: Vasoactive intestinal peptide receptor     Goto   Sponge   NotDistinct   Permalink

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There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach.

AttributesValues
rdf:type
rdfs:label
  • Vasoactive intestinal peptide receptor (en)
rdfs:comment
  • There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. (en)
foaf:name
  • vasoactive intestinal peptide receptor 1 (en)
  • vasoactive intestinal peptide receptor 2 (en)
  • adenylate cyclase activating polypeptide 1 (pituitary) receptor type I (en)
name
dct:subject
Wikipage page ID
Wikipage revision ID
Link from a Wikipage to another Wikipage
Link from a Wikipage to an external page
sameAs
dbp:wikiPageUsesTemplate
OMIM
AltSymbols
  • PACAPR (en)
  • RDC1, HVR1, VAPC1 (en)
  • VPAC2 (en)
symbol
  • ADCYAP1R1 (en)
  • VIPR1 (en)
  • VIPR2 (en)
UniProt
  • P32241 (en)
  • P41586 (en)
  • P41587 (en)
has abstract
  • There are two known receptors for the vasoactive intestinal peptide (VIP) termed VPAC1 and VPAC2. These receptors bind both VIP and pituitary adenylate cyclase-activating polypeptide (PACAP) to some degree. Both receptors are members of the 7 transmembrane G protein-coupled receptor family. VPAC1 is distributed widely in the CNS, liver, lung, intestine and T-lymphocytes. VPAC2 is found in the CNS, pancreas, skeletal muscle, heart, kidney, adipose tissue, testis, and stomach. Vasoactive intestinal peptide (VIP) and pituitary adenylate cyclase-activating peptide (PACAP) receptors are activated by the endogenous peptides VIP, PACAP-38, PACAP-27, peptide histidine isoleucineamide (PHI), peptide histidine methionineamide (PHM) and peptide histidine valine (PHV). “PACAP type II receptors” (VPAC1 and VPAC2 receptors) display comparable affinity for PACAP and VIP, whereas PACAP-27 and PACAP-38 are >100 fold more potent than VIP as agonists of most isoforms of the PAC1 receptor. (en)
Arm
  • p (en)
  • q (en)
band
Chromosome
EntrezGene
HGNCid
RefSeq
  • NM_001118 (en)
  • NM_003382 (en)
  • NM_004624 (en)
gold:hypernym
arm
  • p
  • q
band
  • 14
  • 22
  • 36.3
chromosome
  • 3
  • 7
EntrezGene
  • 117
  • 7434
  • 7433
HGNCid
  • 242
  • 12694
  • 12695
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