The Weirton–Steubenville, WV–OH Metropolitan Statistical Area, also known as the Upper Ohio Valley, is a metropolitan statistical area consisting of two counties in the Northern Panhandle of West Virginia and one in Ohio, anchored by the cities of Weirton and Steubenville. As of the 2020 census, the MSA had a population of 116,903. This puts it at 334th largest in the United States. It is also included in the larger Pittsburgh–New Castle–Weirton, PA–OH–WV Combined Statistical Area.