About: Zenazocine

Facets (new session)
Description
Metadata
Settings
- Rule:
- Inverse Functional Properties:
- "Same As":

About: Zenazocine Goto Sponge NotDistinct Permalink

An Entity of Type : yago:WikicatPhenols, within Data Space : dbpedia.demo.openlinksw.com associated with source document(s)
QRcode icon

http://dbpedia.demo.openlinksw.com/describe/?url=http%3A%2F%2Fdbpedia.org%2Fresource%2FZenazocine

Zenazocine (INN; WIN-42,964) is an opioid analgesic of the benzomorphan family which made it to phase II clinical trials before development was ultimately halted and it was never marketed. It acts as a partial agonist of the μ- and δ-opioid receptors, with less intrinsic activity at the former receptor and more at the latter receptor (hence, it behaves more antagonistically at the former and more agonistically at the latter), and produces antinociceptive effects in animal studies.

Attributes	Values
rdf:type	Thing dul:ChemicalObject chemical substance Drug yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Ketone114926294 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:Phenol114989545 yago:PhysicalEntity100001930 yago:Relation100031921 yago:WikicatKetones drug yago:Substance100019613 yago:WikicatPhenols
rdfs:label	Zenazocina (it) Zenazocine (en)
rdfs:comment	La zenazocine (INN; WIN-42,964) è un oppioide analgesico derivante dalla famiglia del benzomorfano che ha raggiunto la fase III nei test clinici prima che il suo sviluppo venisse definitivamente bloccato e mai messo sul mercato. Agisce come agonista parziale dei recettori μ- e δ-oppioidi, con minore attività intrinseca sui primi e maggiore sui secondi (pertanto agisce in misura preponderante come antagonista sui primi e come agonista sui secondi), e produce effetti nocicettivi su test animali. (it) Zenazocine (INN; WIN-42,964) is an opioid analgesic of the benzomorphan family which made it to phase II clinical trials before development was ultimately halted and it was never marketed. It acts as a partial agonist of the μ- and δ-opioid receptors, with less intrinsic activity at the former receptor and more at the latter receptor (hence, it behaves more antagonistically at the former and more agonistically at the latter), and produces antinociceptive effects in animal studies. (en)
foaf:depiction
dcterms:subject	Analgesics Ketones Opioids Phenols Kappa-opioid receptor agonists Benzomorphans
Wikipage page ID	35583303 (xsd:integer)
Wikipage revision ID	1090048306 (xsd:integer)
Link from a Wikipage to another Wikipage	Partial agonist Benzomorphan Intrinsic activity Δ-opioid receptor Analgesics Ketones Opioids Phenols Kappa-opioid receptor agonists Clinical trial Receptor antagonist Benzomorphans Analgesic International Nonproprietary Name Μ-opioid receptor Opioid Phases of clinical research Tonazocine Receptor agonist Antinociceptive
sameAs	Zenazocine Zenazocine Zenazocine Zenazocine Zenazocine Zenazocine Zenazocine
dbp:wikiPageUsesTemplate	dbt:Analgesics dbt:Drugbox dbt:Opioidergics dbt:Reflist dbt:Short_description dbt:Fdacite
thumbnail	wiki-commons:Special:FilePath/Zenazocine_structure.svg?width=300
ATC prefix	None (en)
c	23 (xsd:integer)
CAS number	74559 (xsd:integer)
ChemSpiderID	8060782 (xsd:integer)
H	35 (xsd:integer)
image	Zenazocine-3D-balls-by-AHRLS-2012.png (en)
IUPAC name	1 (xsd:integer)
legal status	Non-regulated (en)
n	1 (xsd:integer)
O	2 (xsd:integer)
PubChem	9885108 (xsd:integer)
SMILES	O=CCCC3C (en)
StdInChI	1 (xsd:integer)
StdInChIKey	JZFZEWWOIOYBTQ-AXWGZAFASA-N (en)
UNII	8 (xsd:integer)
has abstract	La zenazocine (INN; WIN-42,964) è un oppioide analgesico derivante dalla famiglia del benzomorfano che ha raggiunto la fase III nei test clinici prima che il suo sviluppo venisse definitivamente bloccato e mai messo sul mercato. Agisce come agonista parziale dei recettori μ- e δ-oppioidi, con minore attività intrinseca sui primi e maggiore sui secondi (pertanto agisce in misura preponderante come antagonista sui primi e come agonista sui secondi), e produce effetti nocicettivi su test animali. (it) Zenazocine (INN; WIN-42,964) is an opioid analgesic of the benzomorphan family which made it to phase II clinical trials before development was ultimately halted and it was never marketed. It acts as a partial agonist of the μ- and δ-opioid receptors, with less intrinsic activity at the former receptor and more at the latter receptor (hence, it behaves more antagonistically at the former and more agonistically at the latter), and produces antinociceptive effects in animal studies. (en)
gold:hypernym	Opioid
prov:wasDerivedFrom	wikipedia-en:Zenazocine?oldid=1090048306&ns=0
page length (characters) of wiki page	3029 (xsd:nonNegativeInteger)
CAS number	74559-85-6
FDA UNII code	8WIL6L9U01
PubChem	9885108
foaf:isPrimaryTopicOf	wikipedia-en:Zenazocine
is Link from a Wikipage to another Wikipage of	Benzomorphan List of opioids C23H35NO2 Tonazocine
is foaf:primaryTopic of	wikipedia-en:Zenazocine

Faceted Search & Find service v1.17_git139 as of Feb 29 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 08.03.3330 as of Mar 19 2024, on Linux (x86_64-generic-linux-glibc212), Single-Server Edition (378 GB total memory, 67 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software