The 1965–66 Michigan State Spartans men's ice hockey team represented Michigan State University in college ice hockey. In its 15th year under head coach Amo Bessone the team compiled a 16–13–0 record and reached the NCAA tournament for the second time in its history. The Spartans defeated Clarkson 6–1 in the championship game at the Williams Arena in Minneapolis, Minnesota. as of 2018, the 1965–66 Michigan State team has the worst record of any national champion for Division I (or equivalent) ice hockey.