The 1980 USC Trojans football team represented the University of Southern California (USC) in the 1980 NCAA Division I-A football season. In their fifth year under head coach John Robinson, the Trojans compiled an 8–2–1 record (4–2–1 against conference opponents), finished in third place in the Pacific-10 Conference (Pac-10), and outscored their opponents by a combined total of 265 to 134.