The 2015 McNeese State Cowboys football team represented McNeese State University in the 2015 NCAA Division I FCS football season. The Cowboys were led by tenth-year head coach Matt Viator and played their home games at Cowboy Stadium. They were a member of the Southland Conference. They finished the season 10–1, 9–0 in Southland play to win the Southland Conference title. They went undefeated 10–0 in the regular season. They received the Southland's automatic bid to the FCS Playoffs where they lost in the second round to fellow Southland member Sam Houston State.