The 2020–21 Nigeria Professional Football League (NPFL) was the 50th season of the top flight league in the Nigeria football league system and the 31st since its rebranding. The league started on 27 December 2020 after much delay and concluded on 5 August 2021. Enyimba were the defending champions from the 2019 season but failed to defend their title after finishing third on the table. This season featured the 20 teams from the 2019–20 season as no clubs were promoted nor relegated as the season was cancelled due to the COVID-19 pandemic