The 2020–21 Oregon Ducks men's basketball team represented the University of Oregon during the 2020–21 NCAA Division I men's basketball season. The Ducks, led by 11th-year head coach Dana Altman, played their home games at Matthew Knight Arena as members of the Pac–12 Conference. They finished the season 21-7, 14-4 in Pac-12 Play to finish as regular season champions. They defeated Arizona State in the quarterfinals of the Pac-12 tournament before losing in the semifinals to Oregon State. They received an at-large bid to the NCAA tournament where they advanced to the Second Round due to a positive COVID-19 test from VCU. They defeated Iowa in the second round to advance to the Sweet Sixteen where they lost to USC.