The 516th Strategic Fighter Squadron is an inactive United States Air Force unit. Its last assignment was with the 407th Strategic Fighter Wing at Great Falls Air Force Base, Montana, where it was inactivated on 1 July 1957. The squadron was reactivated in 1953 as part of Strategic Air Command (SAC), flying escort fighters and a few air reconnaissance aircraft. In 1954, the squadron deployed to Japan and provided air defense for the northern part of the islands. It supported SAC bombardment operations until inactivating.