Alkmene (Alcmene), op. 36, is an opera in three acts, with music and libretto by Giselher Klebe. Klebe based the libretto on Amphitryon by Heinrich von Kleist, which in turn was based on Molière's play of the same name, and ultimately draws from the ancient Roman play Amphitryon by Plautus. The composer dedicated the work to his mother, the violinist Gertrud Klebe. The opera was commissioned for the opening of the current building of the Deutsche Oper Berlin where it premiered on 25 September 1961, the second production in that house.