Amesbury CDP was a census-designated place comprising the main urban portions of the city of Amesbury, Massachusetts, in Essex County. With the change of Amesbury's status from town to city in 1996, the delineation of the downtown area as a CDP became unnecessary, and it was no longer used for data collection by the time of the 2010 census. Those details reported here are also included in the aggregate values reported for the entire city; at the 2000 census, the CDP had a total population of 12,327.