Anne Spencer, Countess of Sunderland (née Digby; c. 1646 – 26 April 1715) was the wife of Robert Spencer, 2nd Earl of Sunderland and the daughter of George Digby, 2nd Earl of Bristol and Lady Anne Russell. She had at least five children by Sunderland, only one of whom outlived her: From her own letters, it seems that she had two other children, who died young.