Anne de Mortimer, also known as Anne Mortimer (27 December 1388 – c. 22 September 1411), was a medieval English noblewoman who became an ancestor to the royal House of York, one of the parties in the fifteenth-century dynastic Wars of the Roses. It was her line of descent which gave the Yorkist dynasty its claim to the throne. Anne was the mother of Richard, Duke of York, and thus grandmother of kings Edward IV and Richard III.