Arsen of Tbilisi (Georgian: არსენ თბილელი, Arsen Tbileli), born Iese (იესე) (died 30 November 1812), was a Georgian churchman and scion of the royal line of the Bagratid House of Mukhrani. Arsen was also known by the surname Naibadze (ნაიბაძე) after the title of his father. He was Metropolitan Bishop of Tbilisi with the title of Tbileli from 1795 to 1810 and is known for his controversial role in the Georgian church affairs in the early years of the Russian rule.