Ascot Vale is an inner-city suburb in Melbourne, Victoria, Australia, 6 km (3.7 mi) north-west of Melbourne's Central Business District, located within the City of Moonee Valley local government area. Ascot Vale recorded a population of 15,197 at the 2021 census. Ascot Vale is bounded in the west by the Maribyrnong River, in the north by Maribyrnong and Ormond Roads, in the east by the Moonee Ponds Creek, and in the south by Lyons Road, Epsom Road to the railway line thence generally north-east to Moonee Ponds Creek.