Bernardo Clesio (German: Bernhard von Cles; 1 March 1484 – 30 July 1539) was an Italian Cardinal, bishop, diplomat, humanist and botanist. Born in Cles, in the Prince-Bishopric of Trent, today Trentino, he graduated from the University of Bologna. He later became Prince-Bishop of Trent (1514–1539) and of Brixen (1539), cardinal, and chancellor of Holy Roman Emperor Ferdinand I.