Betsey Guppy Chamberlain (1797–1886) was a textile mill worker who wrote sketches and poetry that were published in The Lowell Offering. Her co-worker, Harriet Hanson Robinson claimed that Chamberlain "had inherited Indian blood" and some sources claim she was Native American; however, there is little identifiable evidence to support the claim. Some of her writing in the Lowell Offering protests the treatment of Native people by the U.S. government.